Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
The incidence of colorectal cancer had been increasing globally, with high‐grade dysplasia in colorectal polyps recognized as a significant precursor to malignancy. This study aimed to determine the prevalence of high‐grade dysplasia among patients with colorectal polyps in a tertiary care hospital setting.A cross‐sectional study was conducted involving 300 patients who underwent colonoscopy and were diagnosed with colorectal polyps at a tertiary care hospital. The presence of high‐grade dysplasia was confirmed through histopathological examination. Data regarding patient demographics, polyp characteristics and histological findings were collected and analyzed. The study found that high‐grade dysplasia was present in a significant proportion of colorectal polyps, particularly among patients aged 50 years and older, with a prevalence of 30% compared to 13.3% in younger patients. The odds of high‐grade dysplasia were notably higher in polyps >10mm in size (OR = 2.3) and located in the colon (OR = 1.9). Gender did not show a significant association with the presence of high‐grade dysplasia. Additionally, while an increasing number of polyps showed a higher prevalence of high‐grade dysplasia, this association did not reach statistical significance. All findings were statistically analyzed to ascertain the strength and significance of these associations, with age, polyp size and location showing notable correlations with the occurrence of high‐grade dysplasia in colorectal polyps. This study provided valuable insights into the prevalence of high‐grade dysplasia in colorectal polyps in a tertiary hospital setting. The findings informed clinicians and health policymakers about the importance of screening and surveillance strategies in the early detection and prevention of colorectal cancer.
How to cite this article:
Sumaiya Shireen, Sumayya Aijaz and Idrees Akhter Afroze. Prevalence of High Grade Dysplasia in Colorectal Polyp Cross Sectional Analysis in Tertiary Care
Hospital.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.3.100.103
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.3.100.103