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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Effectiveness of Intravenous Tranexamic Acid Versus Combination of Tranexamic Acid and per Rectal Misoprostol in Reducing Blood Loss During Caesarean Section: A Prospective Comparative Study

Santanu Sahoo and Debjani Deb
Page: 231-236 | Received 22 May 2024, Published online: 13 Jun 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.18.6.231.236

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Abstract

Postpartum hemorrhage, which can be fatal and is one of the primary causes of maternal mortality globally, is a common complication of Caesarean section delivery, which can result in more complications than a typical vaginal delivery. To ascertain whether tranexamic acid, either by itself or in conjunction with per rectal misoprostol, reduces blood loss and the need for transfusions in patients having caesarean sections up to 24 hours after the procedure and whether doing so is safe. This study is prospective and comparative, with an institutional basis. Study location: Bankura Sammilani Medical College and Hospital, Department of Obstetrics and Gynecology, Post-Natal Ward 2, Emergency Operation Theatre, Bankura, WB. Study period: 18 months. 20 patients (55.6%) in Group A had P0+0 in parity, 10 patients (27.2%) had P1+0 in parity and 6 patients (16.7%) had P2+0 in parity.In Group-B, P0+0 was present in 16 (44.4%) patients, P0+1 was present in 1 (2.8%) patient, P1+0 was present in 9 (25.0%) patients, P1+1 was present in 3 (8.3%) patients, P1+1 was present in 4 (11.1%) patients and P2+0 was present in 3 (8.3%) patients. We came to the conclusion that neither group had any reported complications or adverse effects. In addition to having no negative side effects or complications, tranexamic acid plus 600 micrograms of misoprostol taken rectally statistically reduces the amount of bleeding from placental delivery to 2 hours postpartum.

How to cite this article:

Santanu Sahoo and Debjani Deb. Effectiveness of Intravenous Tranexamic Acid Versus Combination of Tranexamic Acid and per Rectal Misoprostol in Reducing Blood Loss During Caesarean Section: A Prospective Comparative Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.18.6.231.236
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.18.6.231.236