Antibiotics are the most commonly prescribed drugs by various health care professionals. The use of antimicrobials has reduced the incidence of deaths due to various critical infectious diseases. Use of antimicrobial agents (AMAs) forms an important aspect of intensive care units. Infections caused by antimicrobial‐resistant micro‐organisms, Irrational use of antibiotics, high cost and less availability of antimicrobials in ICUs in hospital are the various factors which affect the patient’s outcomes in government hospitals. The study was conducted in Intensive Care Units of a tertiary health care centre for a period of 18 months. Relevant data of 400 patients was collected from the intensive care units. Drugs prescribing data of antimicrobials was collected. All the data collected was entered in a pre‐approved case record form and tabulated using Microsoft Office Excel Software. The frequency of age distribution of the study subjects. Majority of patients were in the age group of 50 years. 306 (76.5%) were prescribed more than 5 drugs, 94 (23.3%) were prescribed less than 5 drugs for the treatment. 68.3% of the patients (n = 273) received a single AMA, whereas 31.8% of subjects (n = 127) required concurrent use of two or more antimicrobials during management in Intensive care units. Most frequently used drugs include Cefotaxime 69.0% (n = 276), metronidazole 29.0% (n = 116), ceftriaxone 7.0% (28), gentamycin 7.0% (28) and ciprofloxacin 5% (n = 20). Empirical therapy with appropriate combinations of commonly used AMAs can be very effective in preventing or controlling various nosocomial infections and significantly contribute in reducing the mortality and improving the survival without producing serious adverse effects or interactions.
V. C. Kavitha, Sandeep Patil and Preeti Dharapur. Study the Existing Prescription Pattern of Antimicrobial Agents and Data for Improvement of
Intensive Care Unit at Tertiary Heath Care Centre.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.32.37
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.32.37