To assess the clinical profiles of patients with persistent severe asthma and evaluate them for the presence of pulmonary hypertension and Cor‐ Pulmonale. 30 consecutive patients with severe persistent asthma which fitted in the criteria were selected. A detailed history was obtained from them and symptom analysis was done. A detailed clinical examination was also done. Presence of pulmonary artery dilatation and other features suggestive of cor pulmonale were also looked for. The clinical profile along with the probable etiology, radiological and electro cardiographic findings were summarized and compared with existing data. Data entry was done in Epidata version 3.1 and analysis will be done using SPSS version 23.0. Minimum age was 40 years and maximum was 80 years, average age was 59.36 years. Female (86.7%) cases were more compared to males (13.3%). Majority of study subjects asthma duration was >20 years i.e. 56.6% and 10‐20 years was 43.4%. Among 30 cases 63.3% (19) was found with mild Pulmonary HTN, 26.7% (8) was moderate Pulmonary HTN and severe Pulmonary HTN was found in 10%. The incidence of Cor Pulmonale was 30%. Patients with severe asthma with duration of 10 years can develop pulmonary arterial hypertension, which is the fore runner for Cor‐pulmonale. Every persistent severe asthma patient with duration of 10 years of asthma should be evaluated for pulmonary arterial hypertension and Cor Pulmonale.
Tula Sri Rajini, Omarbi Lalsiddiqui, Fahad Abdullah and Ashfaq Hasan. A Study of Clinical Profiles of Asthma Patients who Develop Cor‐Pulmonale.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.228.232
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.228.232