Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Quantitative Analysis (Volume and PH) of Activated Platelet in Different Platelet Products by Flow Cytometry From Indore Region of Madhya Pradesh
Gourav Silawat, Ashutosh Singh, Sachin Sharma, Sanjay Silawat and Aman Shakya
Page: 119-123 | Received 15 Oct 2023, Published online: 30 Oct 2023
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Abstract
Platelets are vital to regular hemostasis as well as pathological bleeding and clotting in humans. The cytometer’s subsequent counts may be trusted to be reliable because of this first count’s precision. Clinical investigations involving heart disease and other platelet‐activation illnesses currently make use of flow cytometry. This study aims to conduct quantitative analysis in terms of volume and pH of activated platelet in different platelet products by flow cytometry at tertiary health care center of central India. The present study was cross‐sectional in design, conducted at department of transfusion medicine, MGM Medical College and M.Y Hospital, Indore. In this study a total number of 105 study participants were included. Quantitative analysis (volume and pH) of activated platelet in different platelet products by flow cytometry was performed. The percentage of active platelets on day 1 in the single donor platelet category was 78.8±4.5 while on day 4 it was 74.23±4.8. On days 1 and 4 the percentage of activated platelets was highest in platelets from a single donor. pH on day 1 in platelet rich plasma category was 6.51±0.13 while pH on day 4 was 6.22±0.11. There was decrease in numerical values of pH in each category on day 4 as compared with day 1. Volume and pH of activated platelet in different platelet products declines from day 1‐4 day yet they are still well conserved at the conclusion of that period. Storage conditions determine whether the platelet products may be utilized within 5 days. Activated platelets in various platelet products may be analyzed qualitatively with the use of flow cytometry. Clotting, platelets, activated platelet, flow cytometry.
How to cite this article:
Gourav Silawat, Ashutosh Singh, Sachin Sharma, Sanjay Silawat and Aman Shakya. Quantitative Analysis (Volume and PH) of Activated Platelet in Different Platelet Products by Flow
Cytometry From Indore Region of Madhya Pradesh.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.119.123
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.119.123