Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Coronary artery disease (CAD) is prevalent among Asian Indians, with acute myocardial infarction (AMI) rates rising in India and developing countries. India faces a growing cardiovascular disease burden due to multiple risk factors, including lifestyle (smoking, obesity, physical inactivity) and modifiable factors (lipid disorders, hypertension, insulin resistance). Non-modifiable factors include age, sex and genetics but these alone can't explain the high CAD rates among Indians. Our aim was to correlate Hyperhomocysteinemia with CAD risk factors. We included 189 in-patients in this cross-sectional study. We gathered clinical data and measured serum homocysteine levels. The study included patients with CAD, Ischemic Heart Disease, or a history of cardiac arrest. Males showed a higher CAD prevalence as compared to females. Hyperhomocysteinemia was found to be a significant risk factor in CAD patients. Our study highlights the independent association between elevated homocysteine levels and CAD risk. We established a positive correlation between hyperhomocysteinemia and major CAD risk factors, including Dyslipidemia, diabetes, hypertension and obesity, with statistical significance.
How to cite this article:
Madhav Kadam, Anand Rajput, Minu Bakna and Shashank Tyagi. Serum Homocysteine Level as a Predictive Marker in Patients of Coronary Artery Disease.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.943.946
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.943.946