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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Study on Sputum Bacteriology and Antibiotic Sensitivity Pattern of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in a Tertiary Care Hospital

M.D. Naimul Hoque and Sibes Kumar Das
Page: 630-634 | Received 05 Jul 2023, Published online: 01 Aug 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.630.634

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Abstract

Chronic obstructive pulmonary disease (COPD) is a multisystem condition that mostly affects the lungs. Acute exacerbation of COPD (AECOPD) contributes to the disease's overall severity and irreversible progression. Bacterial infections are the leading cause of AECOPD in India, accounting for more than 40% of all exacerbations. To assess prevalence of bacterial exacerbations of COPD and detect type of bacteria causing AECOPD with its antibiotic sensitivity pattern. This is a hospital based observational descriptive cross sectional study carried out from January 2017 to June 2018, Department of Respiratory Medicine, Medical College Hospital, Kolkata. Total 105 patients were included in this study. In our study smoking habit is not statistically significantly associated with severity of COPD. But it was strongly associated with COPD i.e., COPD is more common in smokers. It was observed that all cases of very severe COPD (100%) and most of the severe COPD (88.24%) developed in smokers and Klebsiella pneunoniae (38.46%), followed by Staphylococcus aureus (23.08%), Streptococcus species (15.39%), Pseudomonas aeruginosa (10.26%), E. coli (5.13%), Acinetobacter species (5.13%) and Enterobacter species (2.56%). Smoking habit was strongly and statistically significantly associated with COPD but statistically not significantly associated with severity of COPD and Most frequently isolated bacteria, Klebsiella pneumoniae was mostly sensitive to Piperacillin/tazobactum, Meropenem, Amikacin, Levofloxacin and Colistin.

How to cite this article:

M.D. Naimul Hoque and Sibes Kumar Das. A Study on Sputum Bacteriology and Antibiotic Sensitivity Pattern of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.630.634
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.630.634