Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis, affecting various systems of the body. It is a leading cause of mortality worldwide. Psychological factors, including stigma, isolation, limited social support, feelings of helplessness and the negative impact of medication side effects, can significantly affect treatment adherence. The aim of this study was to examine the occurrence of major depressive disorder, anxiety disorders and psychosis in patients with Drug Resistant‐Tuberculosis. This study was observational and cross‐sectional, conducted at a single‐center using interviews. Forty‐one consecutive patients diagnosed with drug resistant‐tuberculosis according to the WHO‐RNTCP definition were enrolled from a tertiary care hospital. All patients were interviewed to assess the presence of Major Depressive Disorder, anxiety disorders and psychosis using the criteria outlined in the DSM‐5. The severity of depressive symptoms, anxiety symptoms and psychosis were evaluated using the Hospital Depression Scale, Hospital Anxiety Scale and Brief Psychiatric Rating Scale, respectively. The proportions of participants were compared using the chi‐square test, while the scores from the HADS A, HADS D and BPRS scales were analyzed using the Mann Whitney test and Kruskal‐Wallis test, followed by Dunn's post‐hoc multiple comparisons. The study found that 56% of patients with drug‐resistant tuberculosis had a psychiatric illness. Among these, the frequencies of Major Depressive Disorder, anxiety disorders and psychosis were 41 and 20%, respectively. Patients with drug‐resistant tuberculosis demonstrated a high prevalence of depression, anxiety and psychosis.
How to cite this article:
Sarandha Srivastava, Sameer G. Kotalwar, Jigna Dave, Bharat N. Panchal and Jilan R. Mehta. Psychiatric Illness (Depression, Anxiety, Psychosis) in patients of Drug‐Resistant Tuberculosis.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.216.221
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.216.221