Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
To assess the effect of esmolol and dexmedetomidine in attenuating hemodynamic response to laryngoscopy and endotracheal intubation. 90 adult patients scheduled for elective surgery under general anaesthesia were randomized into three groups of thirty patients each. Parameters such as dose of propofol, HR, SBP, DBP, MAP, RPP, RSS, VAS and duration of laryngoscopy was recorded. The age group 21‐30 years had 8 patients in group A, 9 in group B and 7 in group C, age group 31‐40 years had 7‐6 and 10, 41‐50 years had 9‐8 and 9 and 51‐60 years had 6‐7 and 4 patients respectively. In group A‐B and C, RSS was 2.6‐2.1 and 2.7 respectively. VAS was 4.6‐4.2 and 2.8 respectively. The duration of the laryngoscopy was 10.4‐10.3 minutes and 10.7 minutes. HR (BPM) was 90.2‐91.4 and 89.7, SBP was 132.6‐131.3 mm Hg and 125.5 mm Hg, DBP was 82.5‐82.4 mm Hg and 83.2 mm Hg, MAP was 98.5‐97.3 mm Hg and 98.2 mm Hg respectively. RPP was 116.2‐114.6 mm Hg min X 100 and 115.6 mm Hg min X 100. The dose of propofol was 103.6‐105.2 and 82.5 respectively. Intraoperative intravenous dexmedetomidine reduces the stress response to laryngoscopy and intubation while maintaining hemodynamic stability. Dexmedetomidine 0.5 mcg kg was more effective in suppressing the hemodynamic response to laryngoscopy and intubation, and intraoperative hemodynamic parameters were maintained more consistently. Dexmedetomidine, endotracheal intubation, hypertension.
How to cite this article:
Vivek Prakash, Neha and Taqui Fakhri. A Comparative study of the Effect of Esmolol and Dexmedetomidine in Attenuating Hemodynamic
Response to Laryngoscopy and Endotracheal Intubation.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.532.535
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.532.535