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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Multifactorial Evaluation of Pulmonary Hypertension in Patients with Chronic Kidney Disease: An Institutional Study

M. Dhanamurthy Koppu, Niaz Farhat, Fayaz Shaike and Karnala Sahithi
Page: 336-340 | Received 28 Nov 2023, Published online: 15 Dec 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.12.336.340

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Abstract

This institutional observational study investigates the multifaceted nature of Chronic Kidney Disease (CKD) and its associations with risk factors and cardiovascular parameters, focusing on Pulmonary Hypertension (PH) in a cohort of 70 CKD patients. The study population comprises individuals aged 18 and above, with varying CKD stages, who were screened for PH over the past year. Inclusion criteria encompass CKD patients with confirmed PH diagnosis based on echocardiography or right heart catheterization. Data collected from medical records include demographic information, CKD stage, comorbidities, echocardiographic parameters, treatment regimens and clinical outcomes. PH is defined using standard echocardiographic criteria, and statistical analysis is conducted with a significance threshold of p<0.05. The study included 70 CKD patients with a mean age of 59.83 years. Hypertension (48 patients) and diabetes mellitus (33 patients) were common comorbidities. Hypertension exhibited a strong association with PH (mean association 0.63). Cardiovascular parameters indicated potential left ventricular dysfunction and varied right ventricular performance. Pulmonary and cardiac parameters reflected PH characteristics and echocardiographic assessment in CKD patients with PH revealed elevated Pulmonary Artery Systolic Pressure and right ventricular hypertrophy. This study highlights the complex interplay between CKD, PH and associated risk factors. It emphasizes the importance of considering comorbidities in CKD management. The findings underscore the need for early detection and holistic care approaches, potentially altering the course of both CKD and PH. Chronic Kidney Disease, Pulmonary Hypertension, Cardiovascular Parameters, Echocardiography.

How to cite this article:

M. Dhanamurthy Koppu, Niaz Farhat, Fayaz Shaike and Karnala Sahithi. Multifactorial Evaluation of Pulmonary Hypertension in Patients with Chronic Kidney Disease: An Institutional Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.336.340
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.336.340