Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Vitiligo is an acquired depigmentary condition caused by selective destruction of melanocytes in the basal layer of epidermis. It may involve the hair follicle melanocytes also. To estimate the serum levels homocysteine in patients with vitiligo and control group. 35 patients with vitiligo and 35 age and sex matched controls presented to Dermatology OPD in a tertiary Hospital between January to December 2021 were included in the study. Venous samples were obtained from the study subjects and the levels of homocysteine, vitamin B12 and folic acid were measured by enzyme chemiluminiscent essay method and the data were analyzed using SPSS software version 2020. Serum homocysteine was related to the sex of the patients and type of vitiligo. No significant difference were found in the levels of serum homocysteine between vitiligo patients and controls (p>0.05). No significant relation was found between serum levels of homocysteine and age of the patients, duration of the disease and vitiligo activity (p>0.05). It seems that the presence of a relationship between vitiligo and the serum homocysteine remains controversial and needs to be vigorously investigated.
How to cite this article:
Ullas , Rajeshwari , Amin Syed Moinuddin and Meghana Patil. Study of Serum Levels Homocysteine in Vitiligo Patients and Controls.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.256.260
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.256.260