Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Evaluating the Hemodynamic Effects of Pregabalin Premedication in Laparoscopic Cholecystectomy at a Tertiary Care Center: An Observational Study
Jayashree Sali, Sachin Pawar, Ashok Thorat and Pradeep Wagh
Page: 1059-1063 | Received 12 Aug 2023, Published online: 29 Sep 2023
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Abstract
To evaluate the hemodynamic effects of pregabalin as a premedication in patients undergoing laparoscopic cholecystectomy. An observational study was conducted at a tertiary care center. Patients scheduled for elective laparoscopic cholecystectomy were divided into two groups, one group received pregabalin premedication and the other received a placebo. Hemodynamic parameters such as heart rate, blood pressure and mean arterial pressure were monitored and recorded at multiple time intervals intraoperatively and postoperatively. Patients who received pregabalin premedication exhibited more stable hemodynamics compared to the placebo group. There was a statistically significant reduction in heart rate and mean arterial pressure spikes during pneumoperitoneum in the pregabalin group. Moreover, the post‐operative pain scores were also lower in the pregabalin group. Pregabalin premedication may offer beneficial hemodynamic stability during laparoscopic cholecystectomy. It can be considered a viable option to enhance patient safety during the procedure. Further large‐scale randomized trials are recommended to validate these findings.
How to cite this article:
Jayashree Sali, Sachin Pawar, Ashok Thorat and Pradeep Wagh. Evaluating the Hemodynamic Effects of Pregabalin Premedication in Laparoscopic Cholecystectomy at a Tertiary Care Center: An Observational Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.1059.1063
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.1059.1063