Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Comparative Efficacy of Microneedling with and without Autologous Platelet-Rich Plasma in the Treatment of Striae Distensae: A Prospective, Observer-Blinded Study
B. G. Ramya, Manjunath Durgappa Hatti and Kallappa Herakal
Page: 907-913 | Received 31 Jul 2023, Published online: 17 Aug 2023
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Abstract
Literature on efficacy of microneedling with or without autologous platelet rich plasma (PRP) in striae distensae (SD) is limited. To compare the efficacy of microneedling versus microneedling with autologous platelet rich plasma in striae distensae. In this prospective, observer-blinded comparison trial, a total of 36 patients with SD were included. Each patient received microneedling with autologous PRP on one side and microneedling alone on the other side. The treatments were provided every 4 weeks for a duration of 16 weeks. A follow-up assessment was conducted at the 20th week after the completion of the treatment period. The evaluation of the clinical response to treatment involved the comparison of clinical images taken before and after treatment as well as the assessment of patient satisfaction levels. The assessment of treatment efficacy was conducted with a visual analogue score. The study saw a significant improvement in 51.38% of patients in the microneedling group with a moderate improvement seen in 47.22% of patients. Additionally, one patient in this group showed exceptional improvement. In contrast, the microneedling combined PRP group demonstrated noteworthy improvement in 68.06% of patients (n = 24), while 31.94% of patients (n = 12) in this group experienced good improvement. Significant improvements in striae distensae were observed on each side of the body. Nevertheless, the outcomes shown superior efficacy when microneedling was combined with autologous platelet-rich plasma (PRP) compared to microneedling performed in isolation, with a statistically significant distinction observed between the two approaches. The utilization of microneedling with or without autologous platelet-rich plasma (PRP) has been identified as a viable and effective therapeutic approach for the management of striae distensae, ensuring both safety and efficiency. The combination of microneedling and platelet-rich plasma (PRP) confers additional benefits compared to microneedling as a standalone treatment.
How to cite this article:
B. G. Ramya, Manjunath Durgappa Hatti and Kallappa Herakal. Comparative Efficacy of Microneedling with and without Autologous Platelet-Rich Plasma in the Treatment of Striae Distensae: A Prospective, Observer-Blinded Study.
DOI: https://doi.org/10.36478/10.59218\makrjms.2023.907.913
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218\makrjms.2023.907.913