Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Retrospective Observational Study of comprehensive Staging Surgery in Presumed Early Ovarian Cancer: 5 Years’ Experience of Tertiary Cancer Centre of India
Arunashis Mallick, Arunava Roy, Anik Ghosh, Atanu Sarkar, Vishal Seth and Jaydip Bhaumik
Page: 890-894 | Received 23 Jul 2023, Published online: 15 Aug 2023
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Abstract
The LION'S trial found that patients with advanced ovarian cancer who had therapeutic lymphadenectomy did not gain any advantages. This study sought to determine whether or whether individuals with earlystage ovarian cancer require more involved surgical procedures. This study is a retrospective observational analysis of 106 women diagnosed with ovarian cancer (FIGO Stage I) and treated at the Tata Medical Center in Kolkata with pelvic and para‐aortic lymphadenectomy and complete omentectomy between September 2014 and September 2019. The study will be conducted between September 2014 and September 2019. According to the GOG criteria, a pelvic lymphadenectomy with removal of a minimum of >8 lymph nodes was considered adequate. 39% of patients went through main surgery, while 61% went through completion surgery (23 patients had their hysterectomy completed and 42 patients had their cystectomy completed). High grade serous tissue (n = 30), clear cell tissue (n = 22), low grade serous tissue (n = 5), endometrioid tissue (n = 29), mucinous tissue (n = 10), undifferentiated tissue (n = 3), sero mucinous tissue (n = 5) and poorly differentiated tissue (n = 3). In 77% of pelvic cases and 50% of para‐aortic instances, the lymphadenectomy was effective in removing cancerous lymph nodes. Lymph nodes that had metastasized were located in the pelvis in 6% of individuals and the paraaortic region in 4%. There was a 6% incidence of omental metastases among the patients. In 2% of the patients, metastatic disease was discovered in the para‐aortic nodes as well as the pelvic area. Out of the thirty patients diagnosed with HGSC, three were found to have metastases to the omentum, three to the pelvic nodes and one to the para‐aortic node, as determined by the results of the subgroup analysis. Cancer had not progressed to the pelvic or para‐aortic nodes in any of the twenty‐two CCC patients and only two patients had cancer in their omentums. There was evidence of metastasis to the pelvic nodes in just one of the 29 patients diagnosed with endometrial cancer and there was no evidence of metastasis to the omentum or para‐aortic nodes in any of the patients. One of the five patients with LGSC went on to develop metastases in the pelvic node, while another patient had metastases in the para‐aortic node, despite the fact that there was no deposit in the omentum. In 14% of patients had their cancer stage raised from I to III after further testing. There is a correlation between having a pelvic lymphadenectomy and improved survival. Omentectomy and paraaortic lymphadenectomy did not improve the patient's chances of survival. It is past time that we reevaluate the practice of doing thorough staging surgery on presumptive early cases of ovarian cancer.
How to cite this article:
Arunashis Mallick, Arunava Roy, Anik Ghosh, Atanu Sarkar, Vishal Seth and Jaydip Bhaumik. Retrospective Observational Study of comprehensive Staging Surgery in Presumed Early Ovarian Cancer: 5 Years’ Experience of Tertiary Cancer Centre of India.
DOI: https://doi.org/10.36478/10.59218\makrjms.2023.890.894
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218\makrjms.2023.890.894