Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Clinical Evaluation of Intubating Conditions and Hemodynamic Effects Using Two Doses of Rocuronium Bromide: A Prospective Comparative Study
Isha Naresh Bhagat, Nakul Srivastava and Gurdeep Singh Jheetay
Page: 883-889 | Received 28 Jul 2023, Published online: 15 Aug 2023
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Abstract
To assess the ease of intubation by comparing two doses of Rocuronium bromide for endotracheal intubation. Eighty four patients were selected for the study and the patients were randomized into two groups using chit and box method: Group I: Patients received intravenous Rocuronium: 0.6 mg kg-1 b.wt., intubated at 60 sec and Group II: Patients received intravenous Rocuronium ‐0.9 mg kg-1 b.wt., intubated at 60 sec. Hemodynamic variables: HR, Systolic Diastolic BP and Mean Arterial Pressure were recorded. The intubating circumstances and hemodynamic outcomes of two dosages of Rocuronium bromide were examined in this prospective clinical research. Rocuronium Bromide 0.60 mg per kilogram; 0.90 mg per kilogram were given intravenously. The mean age was among group I and II was 37.86±11.70 and 38.52±7.40 years respectively with 52.4% males and 47.6% females among study population. The mean heart rate before intubation, following intubation, 1, 2, 5 and 10 min post intubation was relevant more in group‐I than group‐II. The mean Systolic blood pressure 1 min post‐intubation and 2 min post‐intubation was more among group I compared to group II. The mean Diastolic blood pressure at 1, 2, 5 and 10 min post‐intubation was more relevant in group II than group I. The mean MAP at 1, 2, 5 and 10 min post‐intubation was more relevant in group II than group1. The mean percentage change in HR, SBP, DBP, MAP and SpO2 among group I was 8.66, 2.59, 7.04, 3.59 and 0.65%, respectively and group II was 2.62, 0.44, 0.13, 1.16 and 0.55%, respectively. Cooper Score 9 was more among group II compared to group I. Cooper Score 6 and 7 was significantly more among group I in comparison to group II. 0.90 mg per kg dose of. Rocuronium 0.90 mg kg-1 is well suited in RSI. 0.60 mg per kg and 0.90 mg per kg rocuronium provide reasonably good intubating situations, although 0.90 mg per kilo provides superior conditions than 0.60 mg per kg.
How to cite this article:
Isha Naresh Bhagat, Nakul Srivastava and Gurdeep Singh Jheetay. Clinical Evaluation of Intubating Conditions and Hemodynamic Effects Using Two Doses of Rocuronium Bromide: A Prospective Comparative Study.
DOI: https://doi.org/10.36478/10.59218\makrjms.2023.883.889
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218\makrjms.2023.883.889