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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Studying the Prevalence of Predominant Bacterial Micro-Organisms in MICU Along-with their Drug Sensitivity and Antimicrobial Resistance Pattern

Prasad S. Korulkar and Shailaja V. Rao
Page: 878-882 | Received 25 Jul 2023, Published online: 14 Aug 2023

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Abstract

Incidence of different organisms in infections acquired in community as well as healthcare set ups vary across different countries and even in different studies. Emergence of new pathogenic strains as well as MDR strains has brought into focus the importance of bacterial surveillance. Further microbial flora and their susceptibility pattern to antibiotics tend to change over time in particular set up. Hence, it is necessary to have knowledge regarding spectrum of microbes and their sensitivity pattern at individual healthcare set up. The above study was conducted at the Medical intensive care unit of a tertiary care hospital from January 2012 to December 2013. Samples of the 883 patients admitted in the MICU were included in this study. All isolates were obtained from a wide range of clinical samples (e.g., urine, pus, blood, sputum, tracheal secretions). Samples were processed for culture and sensitivity testing at department of microbiology. These isolates were studied on the basis of site of infection, characteristics of patients, clinical signs and symptoms, antimicrobial resistance pattern, thus identified as true pathogens. Proportion of gram negative organisms was greater than gram positive organisms. Respiratory isolates were least resistant to Carbapenems, Piperacillin-Tazobactum. Urinary isolates were found least resistant to amikacin and meropenem. For Klebsiella pneumoniae resistance to meropenem increased from 27.30-50.80%. Resistance to amikacin decreased from 67.60-50%. Prevalence of bacteria differs in different health set ups. Antibiotic resistance profile for any bacterial isolate need not be similar in any two health set ups. For rational use of antibiotics, profile of prevalent organisms and their resistance/sensitivity pattern should be known.


How to cite this article:

Prasad S. Korulkar and Shailaja V. Rao. Studying the Prevalence of Predominant Bacterial Micro-Organisms in MICU Along-with their Drug Sensitivity and Antimicrobial Resistance Pattern.
DOI: https://doi.org/10.36478/10.59218\makrjms.2023.878.882
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218\makrjms.2023.878.882