Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
111
Views
9
Downloads
Abstract
Induced Labor is one in which pregnancy is terminated artificially, any time after fetal viability is attained by a method that aims to secure vaginal delivery. Different methods which are widely used for labor induction are vaginal prostaglandins, intracervical prostaglandins, intravenous oxytocin, extra amniotic Foley’s catheterization. Present study was aimed to assess the efficacy of combination of Mifepristone and Misoprostol with respect to Misoprostol alone for induction of labor. Present study was single‐center, prospective, observational study, conducted in pregnant women, singleton pregnancy, cephalic presentation, unfavorable cervix with bishops score <6, reactive FHR pattern with intact membranes, with gestational age between 37 weeks till 41 weeks of gestation requiring induction of labour for various indications. 200 women were divided GROUP A‐ Mifepristone followed by Misoprostol group and GROUP B‐Misoprostol group. In group A patients, mean Bishop’s score after receiving tablet Mifepristone, increased from 2.23‐4.95. Mean induction to active stage interval, mean induction‐delivery interval, requirement of Misoprostol and Requirement for augmentation with oxytocin was less in group A as compared to group B, difference was statistically significant. The incidence of vaginal delivery was slightly higher in group A (70%) versus group B (30%), difference was statistically significant. Outcome of induction of labor in both the groups with success rate of 94 and 95%, no significant difference was noted. NICU admissions were more in group B (14%) as compared to group A (8%). Mifepristone(with or without Misoprostol). Mifepristone along with or without Misoprostol is a safe, effective and convenient alternative to Misoprostol alone in induction of labor in women at term.
How to cite this article:
Shreya , Sarika Madhukar Thakare and Sachin Wankhede. Study of Safety and Efficacy of Mifepristone with Misoprostol and Misoprostol Alone in Induction of Labor in Term Pregnancy.
DOI: https://doi.org/10.36478/10.59218\makrjms.2023.867.872
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218\makrjms.2023.867.872