Chronic ethanol intoxication may lead to loss of subcortical white matter, cerebral atrophy, Wernicke’s encephalopathy, Marchiafava‐Bignami disease, osmotic demyelination syndrome, etc. Moderate/heavy alcohol consumption in older people has been associated with reduced total brain volume, increased ventricle size. Several studies have shown that abstinence can reverse much of the cognitive damage caused by heavy drinking. This is a hospital based, cross sectional case study conducted on all alcohol dependence syndrome patients attending outpatient and inpatient department. A total of 55 patients in the age group of 18‐50 yrs, full filling the inclusion criteria were included in the study which was conducted over a period of 18 months. MR imaging examination was performed on a Siemens Magnetom Avento 1.5 Tesla MR system. Routine brain protocol sequences like Axial‐T1, T2, FLAIR, SWI, DWI, Sagittal‐T2, Coronal‐T2 and MPRAGE were performed. In cortical atrophy, the predominantly involved lobe was frontal lobe which showed more atrophic changes compared to other lobes, followed by parietal and temporal lobe atrophy, least atrophy changes were seen in occipital lobe.
K.G. Naveen, N. Krishnamurthy, H.V. Karthik, V. Deepika and Chetan Divakar Naik. Alcohol Dependence Syndrome Patients: Cortical Atrophy Score on MRI.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.90.94
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.90.94