Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Acute Kidney Injury has been reported to be on rise in both developing and developed countries and it is independently associated with increased mortality and morbidity in children with subsequent development of renal dysfunction. Present study was aimed to study incidence of Acute Kidney Injury in patients admitted in PICU for various causes. This was a prospective observational study conducted under in children within the age group of 2 month to 12 years with length of stay for at least >72 hours in PICU, developed AKI. In this study 131 children developed AKI according to KIDGO criteria giving an incidence of 38.1%. In this study mean age of AKI patient admitted was 3.18±3.11 years. Gender distribution in AKI patient was male 51.9% and female was 48.1%. In present study out of 331 children most common diagnosis at admission to PICU in AKI patients was encephalitis (47.9%), LRTI (21%) and sepsis (18.3%) followed by, severe dehydration (12%), Severe Anemia (7%), complicated malaria (3.1%), Nephrotic Syndrome (0.8%), DKA (0.8%), liver disease (0.8%), were the remaining. As per KDIGO 44 (45.8%) patients were in stage 1, 28 (29.2%) were in stage 2 and 24 (25.0%) were in stage 3. Of 131 patients 32 (18.3%) required inotrope, 11 (45.8%) were discharged, 12 (50%) expired, 1(4.2%) went LAMA, p‐value=<0.001 which considered highly significant. Total 33 (12.2%) patients who were ventilated, 11 (68.75%) went expired, discharged, 5 (31.2%), p‐value=<0.001 which considered highly significant. Mechanical ventilator and Inotropes were the factors which were more likely to predict mortality in AKI with Odds ratio of 46.2 and 27.0 respectively. The incidence of acute kidney injury among critically ill children admitted to PICU was 38.1%. The commonest etiology for patients with acute kidney injury was AES (47.9%) followed by LRTI (21%) and sepsis (18.3%).
How to cite this article:
Vikas Anand and G. Surendiran. Study of Incidence of Acute Kidney Injury in Patients Admitted in PICU for Various Causes.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.668.674
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.668.674