Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Testicular cancer (TCa) is an uncommon tumor primarily affecting young men aged 18‐35 years. Known risk factors include cryptorchidism, a family history of the disease and infertility. This study aimed to explore the impact of certain hematological parameters on the prognosis of testicular malignancies (TM). The study comprised 200 patients diagnosed with TM through physical examination, laboratory tests and scrotal ultrasonography, all of whom underwent radical inguinal orchiectomy. A control group of 200 age‐matched subjects who had bilateral varicocelectomy via an inguinal incision was also included. Hematological and biochemical blood samples were collected the day prior to the radical orchiectomy. Parameters such as the neutrophil‐lymphocyte ratio (NLR), platelet‐lymphocyte ratio (PLR) and lymphocyte‐monocyte ratio (LMR) were calculated as ratios of the specified blood cell types. After the standard radical inguinal orchiectomy, tumor staging was completed based on histological findings, while clinical N and M staging were performed using imaging techniques. The average ages of patients in Groups 1 and 2 were 26.10±7.5 years and 24.9±8.2 years, respectively. Group 1 exhibited significantly elevated neutrophil counts, NLR and PLR, while Group 2 showed statistically significant increases in lymphocyte count, mean platelet volume (MPV) and LMR (p<0.05). Additional data on the pathological findings and follow‐up results for TM patients were also analyzed and the association between hematological parameters and T stage was assessed. The NLR, due to its ease of measurement and cost‐effectiveness, may serve as a valuable adjunct for clinicians. It can aid in the diagnosis of stage I testicular tumors with favorable prognoses, where early diagnosis is crucial, even if it is not the primary diagnostic tool.
How to cite this article:
Dhiren N. Buch, Kushal Kapasi, Ketan D. Mehta and Viraj K. Mehta. The Role of Hematological Parameters in Testicular Tumor Cases.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.652.656
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.652.656