Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Prediction of latency period for women with Preterm premature rupture of membranes (PPROM) is imprecise and duration of the latency period was inversely related to the gestational age at PPROM. This study evaluated the impact of latency period on maternal and fetal outcomes with PPROM. We conducted a cross sectional observational study of women aged 18‐35 years with arrested preterm labour was enrolled. One group received vaginal micronized progesterone as maintenance tocolytic and second group not received any drug for maintenance tocolytic. We have followed all the patients and maternal and fetal outcomes were measured. Majority of the women (32.9%) latency period were 29‐35 days, whereas in Group B most of the women (25.7%) latency period were 8‐14 days, statistically significant (P<0.001). The birth weight was significantly higher in progesterone group as compared to control group. Frequency and duration of NICU admission of birth baby’s was significantly lower in progesterone group as compared to control group (p<0.05). Low Birth Weight babies was higher in control group and neonatal morbidity due to Meconium aspiration syndrome and respiratory distress syndrome was significantly higher in control group (p<0.001). In progesterone group the majority of the women (74.3%) had no side effect and 12.9% complain of itching. Maternal and neonatal outcome were significantly correlated with the latency interval, increasing of latency period associated with the adverse maternal and neonatal outcomes
How to cite this article:
Anita Meena, Jagrati Gupta, Nisha Yadav and Pushpanjali Paraste. Impact of Micronised Progesterone as Maintenance Tocolytic in Affecting Fetal Outcome: A Cross Sectional Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.647.651
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.647.651