Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Polycystic ovarian syndrome (PCOS) is the most frequent endocrine disorder affecting young women and is recognized as a complex condition with multifactorial causes, also linked to heightened metabolic and cardiovascular risks. Both PCOS and thyroid dysfunction share multiple overlapping clinical features and have significant implications for fertility and reproductive health. Hypothyroidism can trigger, exacerbate, or sustain PCOD. This research was designed to assess the prevalence of thyroid abnormalities among PCOS patients. The study included 89 female participants aged 18‐30 years who met the Rotterdam criteria for PCOS diagnosis. Participants were instructed to undergo fasting for the following assessments: fasting glucose, fasting insulin, serum luteinizing hormone (LH), follicle‐stimulating hormone (FSH), thyroid‐stimulating hormone (TSH), serum testosterone, dehydroepiandrosterone and serum prolactin. FSH and LH levels were evaluated on the second or third day of the menstrual cycle. Gynecological ultrasonography was performed to assess ovarian morphology and the presence of multiple cysts. SIn 62% of the cases, the LH/FSH ratio exceeded 2 and 68.54% (61 subjects) showed insulin resistance. Elevated serum testosterone was detected in 65% of cases. The mean TSH level was 4.22±1.78. Subclinical hypothyroidism was observed in 26.97% (24 cases), while overt hypothyroidism occurred in 20.22% (18 cases). Overall, thyroid dysfunction (both clinical and subclinical) was found in 47.19% (42 cases). Thyroid dysfunction is highly prevalent among PCOS patients, suggesting that thyroid screening should be a routine part of PCOS management.
How to cite this article:
Shashank Tyagi, Nidhi Narrey, Swati Gupta and Shalini Nirmal Thagele. Prevalence of Thyroid Dysfunction in Polycystic Ovarian Syndrome Among Indian Women: A Cross‐Sectional Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.620.623
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.620.623