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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Rare Manifestation of Thrombotic Microangiopathy and AKI Following Russell’s Viper Bite: A Case Report in North India

Mansi Jasrotia, Ravi Parihar, Chaitanya Gupta, Surjeet Thappa and Ghanshyam Saini
Page: 558-561 | Received 10 Jul 2024, Published online: 31 Aug 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.9.558.561

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Abstract

Serious health issues are brought on by snake bites, in rural India. In 5‐30% of instances, acute kidney injury (AKI) happens. One of the most prevalent and significant systemic clinical disorders is coagulopathy, which can become worse when there is an important and potentially fatal bleeding episode. Venom‐induced consumption coagulopathy (VICC) is the most prevalent coagulopathy following snakebite and is caused by envenoming Viperid snakes and some elapids. Depending on the specific procoagulant toxin present, procoagulant toxins can activate the clotting pathway and result in a wide range of factor shortages. Therefore, the venom activates vital coagulation factors, and when they are depleted, coagulopathy sets in. Thrombotic microangiopathy occurs in a portion of VICC patients (TMA). This report examines a clinical scenario of TMA linked to snakebite, including its aetiology, diagnosis, treatment, results and response to antivenom and therapeutic hemodialysis. Acute kidney damage (AKI) spectrum, thrombocytopenia in nearly all instances and microangiopathic hemolytic anaemia (seen by schistocytes on the blood film) are the clinical manifestations of snakebite‐associated TMA. Although there is no proof that antivenom specifically prevents TMA, the cornerstone of treatment for snake envenoming is still early antivenom. Patients should have long‐term follow‐up since they are at risk for developing chronic renal disease.

How to cite this article:

Mansi Jasrotia, Ravi Parihar, Chaitanya Gupta, Surjeet Thappa and Ghanshyam Saini. Rare Manifestation of Thrombotic Microangiopathy and AKI Following Russell’s Viper Bite: A Case Report in North India.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.558.561
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.558.561