Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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To Study the Prevalence of Peripheral Vascular Disease in Diabetic Foot Disease and its Influence on Clinical Outcome
Dinesh Singh, Manisha Singh, Rajesh Prajapati, Shyam Gupta and Prashant Shrivastava
Page: 486-492 | Received 20 Jul 2024, Published online: 28 Aug 2024
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Abstract
Diabetic Foot Disease (DFD) is a severe complication of diabetes mellitus characterized by a range of conditions from minor skin lesions to deep infections and gangrene. Peripheral Vascular Disease (PVD), a manifestation of systemic atherosclerosis, significantly contributes to the progression and severity of DFD, complicating the healing process and increasing the risk of infection and limb loss. Understanding the prevalence of PVD in DFD is essential for developing effective management strategies. This study aims to investigate the prevalence of PVD in patients with DFD and evaluate its influence on clinical outcomes, specifically focusing on the need for revascularization, the incidence of amputations, and wound healing processes. This prospective observational study was conducted at the Department of Surgery, J.A. Group of Hospitals and G.R. Medical College, Gwalior, with a sample size of 100 participants. The study included 50 cases and 50 controls, all diagnosed with DFD based on clinical criteria. Patients were divided into groups based on the presence or absence of PVD. Data were collected on demographics, clinical parameters and outcomes, and statistical analyses were performed to evaluate the influence of PVD on clinical outcomes. Among patients with DFD, 28% also had PVD. The presence of PVD was associated with significantly worse outcomes, including higher rates of major and minor amputations and poorer wound healing. The average Ankle Brachial Pressure Index (ABPI) was lowest in the PVD group (0.63), indicating severe arterial obstruction. Statistical analysis confirmed significant differences in clinical outcomes based on the presence of PVD. PVD is prevalent in a significant proportion of DFD patients and is associated with poorer clinical outcomes. Early detection and targeted management strategies, including revascularization and lifestyle modifications, are crucial for improving patient outcomes and preventing complications such as amputations.
How to cite this article:
Dinesh Singh, Manisha Singh, Rajesh Prajapati, Shyam Gupta and Prashant Shrivastava. To Study the Prevalence of Peripheral Vascular Disease in Diabetic Foot Disease and its Influence on Clinical Outcome.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.486.492
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.486.492