Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Psoriasis is a chronic inflammatory skin disorder influenced by genetic, environmental, and psychological factors. While the impact of genetic predisposition on psoriasis is well‐documented, the roles of environmental exposures and psychosocial stress in exacerbating psoriasis severity are less understood. This study aims to assess these factors in an adult population with psoriasis. The aim of the study was to evaluate the influence of environmental and stress‐related factors on psoriasis severity in adults, providing insights into the multifactorial nature of the disease and identifying potential areas for targeted intervention. A cross‐sectional study was conducted at the Department of Dermatology, Venereology and Leprology (DVL) at [Institution Name] over a period of [Specify Duration]. A total of 120 adult patients with clinically confirmed psoriasis were recruited. Data were collected on demographic variables, environmental exposures (living environment, air pollution, humidity, temperature extremes and occupational exposures), and stress levels using the Perceived Stress Scale (PSS). Psoriasis severity was assessed using the Psoriasis Area and Severity Index (PASI). Statistical analysis included descriptive statistics, Pearson correlation, and multivariate linear regression. The mean age of participants was 45.3 years (SD=12.7), with a mean duration of psoriasis of 12.8 years (SD=8.4). 60% of participants resided in urban areas, with 45% experiencing high air pollution exposure. The mean PSS score was 21.8 (SD=6.5), indicating moderate stress levels. A significant correlation was found between higher pollution exposure, stress levels, and increased PASI scores. Multivariate analysis identified air pollution and PSS score as independent predictors of psoriasis severity. This study highlights the significant roles of environmental pollution and psychosocial stress in exacerbating psoriasis severity. The findings suggest that addressing these factors through targeted interventions may improve disease management and patient outcomes. A multidisciplinary approach that includes dermatological care, environmental health and psychological support is recommended for effective psoriasis management.
How to cite this article:
B. Haritha, D. Praneetha, Sruthi Kondaveeti and B. Nikhil. Impact of Environmental Exposures and Psychosocial Stress on Psoriasis Severity: A Cross‐Sectional Study in an Adult Population.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.388.392
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.388.392