Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
A diabetic ulcer is a significant healthcare problem. A chronic diabetic foot ulcer remains difficult to manage., topical application of phenytoin has been used successfully in the management of diabetic foot ulcer. It stimulates the development of granulation tissue formation within 2 to 7 days after beginning treatment and is associated with non‐detectable serum phenytoin levels. Aim of the study is to compare the efficacy of topical phenytoin with conventional wound dressings in healing of diabetic ulcers, in terms of Number of days required for healing, Rate of granulation tissue formation, Quality of graft bed and skin graft up take, Effect on bacterial load and Side effects of topical phenytoin dressing. This was a Prospective Comparative Observational Study which consists of 50 patients admitted with Diabetic Ulcers in Government Medical College, Ongole over a period of one year and There was male predominance as compared to female population in the study (M: F=4:1). The mean rate of granulation tissue formation in study group is 95.93cm of total ulcer surface area and in control group is 98.09cm. The mean graft uptake in the study group is 99.03cm and in the control group is 97.61cm. The total number of hospital stay for the patients, mean number of days in study group was 27.8 days and control group was 31.3 days. 45% of study group showed negative culture sensitivity at the end of 14 days whereas in control group it was 37%. Pseudomonas was the commonest organism in the study (68%) followed by MRSA (52%). Number of ulcer dressing changes were less in phenytoin group (10.68) as compared to povidone iodine group(16.52). Thus reducing the ulcer size does affects the man working hours of the patient. Early return to work does reduce the financial burden on the patient. The use of phenytoin dressing accelerates the rate of wound healing in diabetic ulcers.
How to cite this article:
P. Vijayendra, A. Anusha, J. Venkateswara Naik and David Salivendra. A Comparative Study of Topical Phenytoin Versus Conventional Wound Care in Diabetic Ulcers.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.284.288
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.284.288