Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Rh Negative pregnancy is a high risk pregnancy. Rh Incompatibility is exposure of Rh Negative mother to Rh Positive fetal blood during pregnancy or delivery leading to maternal antibody formation against foreign Rh antigen that cross placenta and destroy Rh positive fetal erythrocytes resulting in fetal Alloimmune Induced Haemolytic Anaemia. There are many fetal and maternal complications due to Rh Negative pregnancy. So Anti‐D Immunoglobulin should be given within first 72 hrs of delivery/sensitizing event. Prophylactic antenatal Anti‐D Immunoglobulin is given at 28 weeks. Aim of the Study is to assess the Incidence, Maternal and Perinatal outcomes in Rh Negative Pregnancy. This was a Prospective Study done in 60 cases, over a period of 1 year at ACSR Government General Hospital, Nellore, Andhra Pradesh, India. In our study Prevalence of Rh Negative Pregnancy was 2.36%.Highest Prevalence was found to be in 21‐25 yrs age group. Most common blood group was O Negative (51.6%), followed by B Negative (25%). 41.66% were Primi which predominated. Risk factors that were associated were Preeclampsia (6.6%), Gestational Diabetes Mellitus (1.66%), Polyhydramnios (5%), Oligohydramnios with Intrauterine Growth Retardation (3.34%). 70% mothers had Normal Vaginal Deliveries. 25% underwent Caesarean Section. Live births were 96.6%., Still birth1.6%, Intrauterine Fetal Demise 1.6%. One early Neonatal death was reported. Majority of newborn APGAR Score was 10 with 78.3%. Of 60 mothers 40% mothers took Antenatal Prophylaxis., which needs to be improved. All mothers of babies with Rh Positive blood group were given Postnatal Prophylaxis. So there must be increased awareness among doctors and patients about Antenatal Prophylaxis at 28 weeks or after any sensitizing event.
How to cite this article:
Madhuri Ampilli, Kavitha Mettu, Bhavani Koppala and Mary Snigdha Vanka. Maternal and Foetal Outcome in RH Negative Pregnancy AT A Tertiary Care Centre.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.220.224
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.220.224