Glanzmann thrombasthenia is a rare inherited autosomal recessive bleeding disorder characterized by abnormal platelet aggregation and clot retraction. Women with GT may experience prolonged, heavy, or irregular menstrual bleeding, especially at menarche. This bleeding can be difficult to manage and may not respond to treatments like packed red blood cells, platelet concentrates, or recombinant activated factor VII (rFVIIa). We are presenting a case of a 15year old girl presenting with Glanzmann thrombasthenia with complaints of heavy menstrual bleeding. As such, the management of these individuals continues to be complicated. The only effective treatment for GT is still bone marrow transplantation, however gene therapy is being investigated more and more as a potential future option.
Madderla Sowmya, Shreedevi Kori, Dayanand Biradar, Subhash Mudanur, Shobha Shiragur and Aruna Biradar. Glanzmann’s Thrombasthenia‐A Rare Cause Of Abnormal Uterine Bleeding.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.9.130.133
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.9.130.133