Doppler velocimetry is a rapid noninvasive test that provides valuable information about the hemodynamic situation of the fetus and is an efficient diagnostic test of fetal jeopardy that helps in management of high‐risk pregnancy. Present study was aimed to assess cerebroplacental ratio at 35‐37 weeks of gestation in the prediction of adverse perinatal outcome. Present study was single‐center, prospective, observational study, conducted in pregnant women, >18 years of age, Singleton pregnancy, undergone a third trimester USG Doppler at 35‐37 weeks. The PI ratio were measured for both UA and MCA and Cerebral placental ratio (CPR) was calculated. A low cerebroplacental ratio was defined as <1. Out of the total 283 cases studied, low cerebro‐placental ratio (<1) was seen in 33.9% cases. Incidence of MSL was 55.2% in cases with low CP ratio as compared to 36.4% in cases with normal CPR, difference was statistically significant (p<0.01). There is a significant statistical association (p value <0.01) between mode of delivery and low /normal CP ratio, with higher incidence of Caeserean section in cases with low CPR ratio. Normal Doppler findings were seen in 57.2% cases with normal CP ratio as compared to only 9.4% cases with low CP ratio. Combined utero‐placental and cerebro‐placental insufficiency on Doppler was seen in 52.1% cases of low CP ratio as compared to 19.3% cases with normal CPR which was statistically significant (p<0.01). Overall sensitivity and specificity of CP ratio (<1) to predict adverse perinatal outcome was 53.4% and 98.1% while PPV and NPV was 97.9% and 56.1%. Overall accuracy was 70.3%. Area under ROC to predict adverse perinatal outcome was 0.734 (95% CI: 0.67‐0.79, p<0.01). Cerebro‐placental ratio can predict adverse perinatal outcome in uncomplicated pregnancies at term with good accuracy.
Anagha Anil Jinturkar, Swati Ramchandra Gurav and Meghana Biju. Study of Assessment of Cerebroplacental Ratio at 35‐37 Weeks of Gestation in the Prediction of Adverse Perinatal Outcome.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.10.16
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.10.16