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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Cross‐Sectional Study on the Utility of Liquid‐ Based Cytology Versus Conventional Pap Smear in Cervical Cancer Screening

Kusuma Nikhila, Srigiri Sanjeevkumar, Pavuluri Neelima and Rachakonda Nagaspandana
Page: 580-584 | Received 26 Apr 2024, Published online: 28 Jun 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.6.580.584

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Abstract

Cervical cancer screening is a critical public health strategy that reduces the incidence and mortality of cervical cancer. This study compares the diagnostic effectiveness, sample adequacy and cost implications of Liquid‐ Based Cytology (LBC) versus Conventional Pap Smear in cervical cancer screening. A cross‐sectional study was conducted on a sample of 140 women attending a tertiary care center for cervical cancer screening. Participants were screened using both LBC and Conventional Pap Smear methods. The main outcomes measured were the rate of positive cases, sensitivity and specificity of each method, the rate of unsatisfactory samples and an initial assessment of cost‐effectiveness. LBC detected a higher percentage of positive cases (25.7%) compared to the Conventional Pap Smear (20%), although this was not statistically significant (OR 1.35., 95% CI 0.78‐2.34., p=0.28). Sensitivity was higher for LBC (20%) than for Conventional Pap Smear (13.6%), with a nearsignificant difference (OR 1.61., 95% CI 0.92‐2.83., p=0.10). LBC also demonstrated a significantly lower rate of unsatisfactory samples (5%) compared to Conventional Pap Smear (10%) (OR 0.48., 95% CI 0.19‐1.22., p=0.12). The cost‐effectiveness analysis suggested higher costs for LBC which may not be justified by the marginal increases in effectiveness observed. While LBC shows a trend towards improved detection rates and reduced rates of unsatisfactory samples, these benefits may not outweigh the additional costs associated with its use in all settings. The decision to implement LBC should consider both clinical benefits and economic implications.

How to cite this article:

Kusuma Nikhila, Srigiri Sanjeevkumar, Pavuluri Neelima and Rachakonda Nagaspandana. A Cross‐Sectional Study on the Utility of Liquid‐ Based Cytology Versus Conventional Pap Smear in Cervical Cancer Screening.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.6.580.584
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.6.580.584