Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Nosocomial wound infections are additional afflictions to patients which are associated with increased morbidity, mortality, increased hospital stay and treatment cost. P. aeruginosa is widespread in natural environments and an opportunistic pathogen causing variety of nosocomial infections including wound infections. It is found to be intrinsically resistant to many classes of antimicrobial agents. Two hundred specimens of pus were collected from patients with nosocomial wound infections. The specimens of pus were immediately inoculated on Blood agar and MacConkey’s agar. The inoculated plates were incubated at 37EC for 24 hours. The colonies showing typical morphology of P. aeruginosa on Blood agar and MacConkey’s agar, are identified by using biochemical reactions were processed further for antimicrobial susceptibility testing. The most common pathogen isolated was Staph. aureus 71 (30.87%) followed by P. aeruginosa 63 (27.39%), Klebsiella spp. 31 (13.48%), Proteus spp. 21 (09.13%), E. coli 17 (07.39%), Citrobacter spp. 13 (05.65%), Acinetobacter spp. 9 (03.91%) and Strep. pyogenes 5 (02.17%). Among the antimicrobial agents used, the most effective antimicrobial agent found was imipenem (98.41%), followed by amikacin (65.07%), meropenem (57.14%), cefoperazone (53.96%), gatifloxacin (49.20%), ceftazidime (46.03%), ciprofloxacin (44.44%), gentamicin (39.68%) and piperacillin (12.69%) Nosocomial wound infections caused by P. aeruginosa continues to be an important problem to be thought seriously. Improper, unnecessary and indiscriminate use of antimicrobial agents encourage development of resistance and should be avoided. P. aeruginosa isolated from nosocomial wound infections, which are resistant to multiple antibiotics should be paid special attention.
How to cite this article:
Milind Davane, Sanjivani Mundhe, Basavraj Nagoba and Asha Pichare. Nosocomial Wound Infections with Special Reference to Pseudomonas Aeruginosa.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.5.583.588
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.5.583.588