Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Clinicodemographic Profile, Treatment Approaches and Outcome in Necrotizing Fasciitis: A Prospective Study
Rohit Dubey, Manohar Kumar Malviya, Abida Sabreen, Rajkishore Singh and Neeraj Kumar Jain
Page: 183-186 | Received 15 Apr 2024, Published online: 30 May 2024
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Abstract
Necrotizing fasciitis (NF) is a severe infection characterized by rapid spread along fascial planes, leading to extensive tissue necrosis. Although rare, NF is a life‐threatening condition that imposes considerable financial burdens on both individuals and healthcare systems. Despite its severity, few studies have explored the correlation between demographic and clinical features, treatment and outcomes of NF. Therefore, this study aimed to investigate these correlations. This study included patients aged over 18 years who were clinically diagnosed with NF admitted to an Indian tertiary care medical teaching hospital. Patients with other soft‐tissue infections such as cellulitis and abscesses were excluded from the study. For each patient, a thorough history was taken and a detailed clinical examination was performed. Data were collected from the case records of patients diagnosed with NF. The most affected age group was 51‐60 years. Of the 124 patients, 124 were male and 30 were female, yielding a male‐to‐female ratio of 4.13:1. The lower limb was the most commonly involved site. Trauma was the most common risk factor for NF, followed by diabetes. Piperacillin combined with tazobactam was the most commonly used antibiotic. Among the 154 patients, 31 underwent amputations, 41 developed septic shock and subsequently died, 16 required skin grafting. The mean duration of hospital stay was 12.56 days. The mortality rate was 26.62%. The study observed a high mortality rate among NF patients., however, significant improvements were noted in survivors. Early surgical intervention (within 72 hours) coupled with broad‐spectrum antibiotics are associated with favorable outcomes. Prompt surgical intervention and comprehensive care are crucial in reducing the morbidity and mortality associated with NF.
How to cite this article:
Rohit Dubey, Manohar Kumar Malviya, Abida Sabreen, Rajkishore Singh and Neeraj Kumar Jain. Clinicodemographic Profile, Treatment Approaches and Outcome in Necrotizing Fasciitis: A Prospective Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.5.183.186
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.5.183.186