Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
By identifying the key determinants and patterns of SSIs, this research seeks to contribute to improved infection prevention and management protocols in the region of Western Uttar Pradesh. This study aimed to assess the prevalence, microbial profile and antibiotic susceptibility pattern of post‐operative SSIs in a tertiary teaching hospital in the region. In a cohort of 282 patients presenting with post‐operative wound infections, 196 exhibited bacterial growth. The majority (57%) of pus samples were collected from the surgical wards. The prevalence of Gram‐negative bacteria was notably higher than that of Gram‐positive bacteria at rates of 128 isolates (59.2%) versus 88 isolates (40.8%). The predominant pathogens identified included Staphylococcus species (86 isolates, 39.8%) and Escherichia coli (52 isolates, 24%). E. coli demonstrated the highest sensitivity to Tigecycline (100%), followed by Chloramphenicol (92.8%), Imipenem (85.5%), Amikacin (72.2%). Staphylococcus aureus displayed complete sensitivity (100%) to Vancomycin, Linezolid and Teicoplanin, underscoring their efficacy as first‐line treatments for infections caused by this organism. Additionally, high susceptibility was observed to Mupirocin (95.3%), Rifampicin (95.3%) and Clindamycin (93.7%). The sensitivity data provides critical guidance for empiric antibiotic selection and underscores the importance of continued surveillance to monitor emerging resistance trends. Findings also emphasize the continued efficacy of key antibiotics against Gram‐positive cocci while reinforcing the importance of ongoing monitoring to detect potential shifts in resistance patterns.
How to cite this article:
Rohit Pandey, Pratiksha , Sapna Chauhan, Aakansha Gupta and Shewtank Goel. A Prospective Study of Post‐Operative, Surgical Site Infections (SSIS) from a Teaching Hospital of Western Uttar Pradesh.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.747.750
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.747.750