Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Acne vulgaris is a prevalent dermatological condition throughout adolescence. The extensive and indiscriminate application of antibiotics for acne therapy has led to the proliferation of resistant bacterial strains and subsequent treatment failure. The objective of the study was to examine the microbiological spectrum in acne vulgaris and assess its susceptibility to commonly utilized antibiotics for acne treatment. Study was conducted in collaboration with microbiology and dermatology departments at a tertiary care teaching hospital in Western Uttar Pradesh over a period of six months. The samples were grown separately on blood agar and Muller‐Hinton media. The cultures were subsequently incubated under aerobic and anaerobic conditions for a duration of 2‐7 days. Bacteria were discovered and their resistance to prevalent antibiotics was assessed following conventional protocols. Staphylococcus epidermidis and Staphylococcus aureus were the most prevalent under aerobic conditions, detected in 48% and 45% of the samples, respectively. Conversely, under anaerobic conditions, Propionibacterium acnes was predominant, present in 35% of samples, whereas Staphylococcus aureus was found in 40%. Rifampin demonstrated the highest sensitivity rate (86%), making it a potentially effective treatment option. Benzoyl peroxide also exhibited significant sensitivity (72%), particularly when combined with other antibiotics. Study underscores the dynamic nature of acne‐associated bacteria and the growing challenge of antibiotic resistance. Rifampin emerged as a highly effective treatment option, particularly when combined with other agents. The findings advocate for judicious antibiotic use and the implementation of combination therapies to combat resistance.
How to cite this article:
Rohit Pandey, Pratiksha , Sapna Chauhan, Aakansha Gupta and Shewtank Goel. Microbial Landscape and Drug Resistance in Acne Vulgaris: A Cross‐Sectional Study from Rural Indian Population.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.743.746
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.743.746