Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Aim of the study is to evaluate if elevated liver enzyme levels can be used as an early predictor of severe dengue fever. Of the 300 children who participated in the study, the most prevalent age range was determined to be 6‐12 years, with 144 boys and 156 girls. 55% of the study's participants had dengue fever and showed warning signals. 207 (or 69%) of the 300 kids tested positive for IgM Dengue. 297 out of the 300 kids lived. The mortality rate was low, only 1%, being a tertiary care facility with high‐quality care and protocol‐based management in accordance with WHO 2015 criteria. This is consistent with research done in South East Asia, where a death rate of 1% was also seen. Based on the severity of thrombocytopenia, the study population was separated into 6 groups. Only mild thrombocytopenia (80,000‐1,50,000) was present in 29%. A significant p value of <0.05 revealed a positive link between the severity of the disease and the severity of the thrombocytopenia. A significant correlation between the level of SGOT increase and IgM Dengue positive was noted. Additionally, a linear association between the degree of SGOT increase and the seriousness of the sickness was discovered. It was discovered that normal SGOT levels have a strong negative predictive value. Therefore, an early indicator of the severity of the disease can be the rise of the SGOT liver enzyme. Elevated SGPT levels were found to be significantly associated with severe Dengue. The degree of SGPT elevation and sickness severity were found to be correlated linearly. Therefore, increased SGPT levels can be used to estimate the severity of a disease.
How to cite this article:
Rajiv Kumar, Nagesh Sali and John Basha Shaik. Study on Liver Enzymes as an Early Predictor of Complicated Dengue Fever in a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.709.712
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.709.712