Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Preeclampsia affects 10 million women each year, accounting for 76,000 maternal deaths. Since the one and only effective treatment is delivery of the fetus, it has therefore lead to iatrogenic preterm deliveries and thus causing 500,000 neonatal deaths each year. Preeclampsia also affect s neonatal morbidity to a great extent by causing intrauterine growth restriction, oligohydramnios, iatrogenic low birth weight preterm babies, all of which babies require intensive care. In western countries, incidence is 2‐7% out of which 0.1% of them progress to develop seizures, known as eclampsia. To study the efficacy of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in predicting preeclampsia at early second trimester. (13‐20 weeks). To study and compare neutrophil to lymphocyte ratio and platelet to lymphocyte ratio measured at 13‐20 weeks (before the development of disease) among normotensive, non‐severe preeclampsia and severe preeclampsia women. Case control study. 300 Neutrophil and lymphocyte levels are measured using automated cell counter and the corresponding ratios are measured. All enrolled patients are regularly followed up in OPD in their second and third trimesters. Patients who developed preeclampsia are taken as CASES. 5ml venous sample is taken for those who developed disease. Out of 300 women, 68 women developed preeclampsia (52 non severe and 16 severe preeclampsia respectively) and 232 were normotensive. NLR and PLR have shown promising results in many studies on early prediction of preeclampsia. These markers are a part of routine antenatal investigation profile, they are very simple, rapid, non‐invasive and easily available predictor tool developed so far in the early prediction of the disease.
How to cite this article:
K. Bhuvaneshwari, P.R. Rani, S. Suganthi, Suguna , Chinnaiyan Ponnuraja and S. Padmanaban. Role of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio as Predictors of Preeclampsia.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.474.479
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.474.479