Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Children with sickle cell anemia most often struggle with severe, ongoing discomfort. Most children with sickle cell anemia go through at least one pain crisis year and these crises have a detrimental effect on the kids. Compared to people without pain crises, they are more likely to suffer from despair, a worse quality of life, more frequent absences from school, and strained relationships with their peers. Additionally, as pain crises account for the majority of hospitalizations and emergency department visits among children with sickle cell anemia, they constitute a significant financial and health care services utilization burden. To study the clinical profile of Vaso‐occlusive painful crisis in children diagnosed with sickle cell anemia on hydroxyurea. This is an Observational cross‐sectional study and the study Duration was from January 2021 to June 2022. The total Sample Size was 48 patients. In our study it was observe that 24(50%) out of 48 children were started on hydroxyurea within one year of admission. Whereas 17 (35.4%) children were on hydroxyurea since >3 years. In those groups who were on hydroxyurea less than 1 year, majority were below 5 year of age 5(100%). The p value (p=0.0075) was statically significant. Hydroxyurea therapy effectively reduces the frequency and severity of VOC in children with SCA, leading to improved quality of life and clinical outcomes. Early initiation of hydroxyurea and close monitoring of therapy adherence are critical in managing SCA in paediatric populations. Further longitudinal studies are recommended to assess long‐term benefits and potential side effects.
How to cite this article:
Yogesh Ramdas Chavan and Jayant Acharya. Study of Clinical Profile of Vasoocclusive Painful Crisis in Children of Sickle Cell Anemia on Hydroxyurea.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.421.425
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.421.425