Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, expectoration) due to abnormalities of airways (bronchitis, bronchiolitis) or alveoli (emphysema) that causes persistent, often progressive airflow limitation. Post Bronchodilation FEV1/FVC <0.70 confirms the diagnosis of COPD. Neutrophil Lymphocyte Ratio is a tool which helps to find out the severity of disease and also the activity status of the disease in COPD patients. NLR can also predict the prognosis of the COPD patient by comparing it with the BODE index. To calculate Neutrophil‐Lymphocyte Ratio and differentiate between Stable and Acute Exacerbation of COPD. The study was performed at AIMSR, Bathinda wherein 55 patients each of Stable COPD and Acute Exacerbation of COPD (AECOPD) were enrolled. The Neutrophil Lymphocyte Ratio was calculated from Haemogram of patients. Continuous variables were summarized as mean with standard deviation and compared between groups using Unpaired t test. In Stable COPD, the mean NLR of patients was 2.0038±.2070 and in Acute Exacerbation COPD, the mean NLR of patients was 4.8022±.3822. NLR is an easily available biomarker of inflammation and can be used as a predictor of exacerbation in patients of COPD. The severity of the exacerbation state can be stated by the NLR value without the help of spirometry. NLR can also predict the prognosis of the COPD patient by comparing it with the BODE index.
How to cite this article:
Shivam Salaria, Arsh Kumar Garg, Avneet Garg and Sweta Gupta. Evaluation of Neutrophil Lymphocyte Ratio In Patients of Stable and Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.210.213
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.210.213