Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Short stature is one of the most common concerns in pediatric health, with causes that range from physiological to pathological, each accounting for roughly half of the cases. This study aims to explore the clinical profiles of children presenting with pathological short stature, with a particular focus on identifying its diverse causes, including syndromic conditions. By investigating the full spectrum of underlying factors, the study seeks to enhance understanding and management of pathological short stature in pediatric populations. Retrospective study was conducted in outpatient clinic of endocrinology unit in dept of medicine at SMHS Hospital, Karan Nagar, Srinagar J and K, where the data of children who met the inclusion criteria were collected from the case records of 1.5 years period from Feb 2022 to August 2023. Data collected was tabulated and analyzed using appropriate statistical methods. In the present study, the overall incidence of short stature was found to be 9.7%. Among the cases, proportionate short stature accounted for 91%, while disproportionate short stature comprised 9%. Etiologically, pathological short stature (68%) was more prevalent than physiological short stature (32%). Within the pathological category, genetic causes were the most common, contributing to 41.2% of cases, followed by endocrine disorders (17.6%), central nervous system involvement (11.8%), respiratory system issues (11.8%), renal conditions (11.8%) and haematological disorders (5.9%). Among the 33% of cases categorized as physiological short stature, nutritional deficiency was the most common accounting for 37.5% of cases followed by familial history of short stature (25%) and delayed puberty (25%). Genetic abnormalities and endocrine disorders are the most common causes of pathological short stature. Given that many of these conditions can be effectively treated when identified early, a thorough evaluation is essential for timely diagnosis and intervention.
How to cite this article:
Zhahid Hassan Baigh, Dara Sudhakar, Iqra Fayaz and Irfan Ali. Pathological and Syndromic Short Stature in Children: Clinical and Etiological Profile.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.71.76
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.71.76