Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
92
Views
9
Downloads
Abstract
Stroke of all types rank second as a cause of death and is the leading cause of disability in adults. Elevated D Dimer levels is a reflection of ongoing thrombus formation in blood vessels. Present study was aimed study correlation of plasma d‐dimer levels with the severity of acute ischemic stroke at a tertiary care hospital. Present study was cross‐sectional descriptive study, conducted in patients with sudden onset of focal neurological deficit with or without radiological evidence of ischemic stroke. Patient was subjected to relevant blood and radiological investigations. Sample for D‐dimer levels was drawn at admission. D‐dimer levels were correlated with the severity of stroke. Severity of stroke was assessed using the NIHSS scale. Out of 75 subjects, 14(18.70%) suffered from Minor Stroke, 42(56.00%) suffered from Moderate Stroke, 4(5.30%) suffered from Moderate to Severe Stroke, and 15(20.00%) from Severe Stroke. There was a significant difference in the mean age among the groups, as p<0.05. 22(29.30%) were females and 53(70.70%) were males. There was significant association between presence of comorbidities and severity of stroke. It was observed that the mean D‐Dimer increased significantly with severity of stroke. It was observed that the mean NIHSS increased significantly with severity of stroke. Significant, highly strong, positive correlation was observed between D‐Dimer and HBA1C, r=0.928, p<0.05. Significant, strong, positive correlation was observed between D‐Dimer and RBS, r=0.789, p<0.05. Significant, moderate, positive correlation was observed between D‐Dimer and Triglycerides, r=0.512, p<0.05. Significant, moderate, positive correlation was observed between D‐Dimer and Total Cholesterol, r=0.544, p<0.05. Significant, moderate, positive correlation was observed between D‐Dimer and LDL, r=0.466, p<0.05.Significant, weak, negative correlation was observed between D‐Dimer and HDL, r=0.260, p<0.05. D‐dimer levels can be measured in acute ischemic stroke to understand its severity and to predict its functional outcome.
How to cite this article:
Arundhati R. Chitnis, J. Chandan, H.D. Rachan Raj and Kamsala Chaitanya. Study of Correlation of Plasma D‐Dimer Levels with the Severity of Acute Ischemic Stroke at a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.453.458
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.453.458