Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that can affect multiple organ systems, including the eyes. Ocular manifestations are a significant concern as they can lead to serious visual impairments if not properly managed. To evaluate the prevalence, types, and impacts of ocular manifestations in patients with SLE and to analyze their relationship with disease severity. This retrospective observational study reviewed the medical records of 200 patients diagnosed with SLE at a tertiary care center. Ophthalmologic assessments were analyzed to identify the prevalence and types of ocular manifestations. Statistical analyses included the calculation of odds ratios (ORs), 95% confidence intervals (CIs) and P‐values to determine the significance of the findings. The most common ocular manifestations identified were uveitis (56%), keratoconjunctivitis sicca (18.5%), scleritis (17%) and retinal vasculitis (8.5%). The severity of SLE was strongly correlated with the incidence of severe ocular conditions. Ocular manifestations were significantly associated with reduced quality of life, particularly in patients with severe manifestations. The statistical analysis indicated significant relationships between SLE activity and the types of ocular manifestations (P<0.05). Ocular manifestations in SLE patients are common and vary widely in type and severity. They are strongly associated with overall disease activity and significantly impact patients' quality of life. Regular ophthalmological assessments are essential for the early detection and management of these complications in SLE patients.
How to cite this article:
K. Kavya Lahari, Mohammed Azhar Chisti, Azeemunisa Mohammed and A. Venkata Satish. Ocular Manifestations in Patients with Systemic Lupus Erythematosus.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.438.442
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.438.442