Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Fentanyl was first synthesized as an intravenous anaesthetic by Paul Janssen in 1960. It is a potent agonist of the μ‐opioid receptor which is responsible for its analgesic and sedative properties. It is almost 100 times more potent than morphine and has a relatively wide therapeutic index, which makes it a very safe anaesthetic drug when monitored carefully. Drug patches were applied to patients 12 hours before proposed surgery in both groups after noting baseline hemodynamic parameter. Patients were premedicated with Antacids and Anxiolytics i.e., Tab Ranitidine 150mg po and Tab Alprazolam 0.5 mg PO HS under strict aseptic precautions 25g Quincke’s Babcock spinal needle was inserted in L3‐L4 and 0.5% (H) bupivacaine was injected. Adequate block was achieved. When SBP was compared between two groups at different time intervals, p value was >0.05 and so the results were statistically insignificant. When DBP was compared between two groups at different time intervals, p value was >0.05 and so the results were statistically insignificant.
How to cite this article:
Rohith Jamadar, Sahana Hiremath, S.M. Ashish and Dhanashree Vitthal Nandana. Transdermal Buprenorphine Patch or Transdermal Fentanyl Patch in Lower Limb Surgeries: Hemodynamic Changes.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.419.422
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.419.422