Severe acute respiratory infection caused by SARS-CoV-2 is a major public health concern worldwide. Diseases can range in severity from minor to fatal. An important public health technique for tracking changes in circulating viruses, identifying aetiologies to explain the disease and serving as a warning system for future pandemic viruses is the surveillance of hospitalized patients with severe acute respiratory infections (SARI). Our objectives are to ascertain the SARS-CoV-2 positive rate in SARI cases and to investigate the patient's clinical and epidemiological features in more detail. 200 individuals with severe acute respiratory illnesses who were admitted to tertiary care hospitals participated in a prospective study. Every patient's clinical, demographic, epidemiological, risk factor and co-morbidities were documented. Real-time reverse transcriptase (RT-PCR) testing was used to detect SARS-CoV-2 in oropharyngeal and nasopharyngeal samples that were obtained. 51 (25.5%) of the 200 SARI patients had positive SARS-CoV-2 tests. Males were primarily affected (52.94%)., the age group of 41-60 years old had the maximum number of cases (54.90%). The most typical presentation symptoms were sore throat (56.86%), dyspnea (82.35%), fever (100%) and cough (86.27%). Hypertension (56.86%), Diabetes Mellitus (33.33%), Chronic Obstructive Pulmonary Disease (13.72%) and Coronary Artery Disease (9.8%) were the comorbidities linked to COVID-19. Over 30% of the patients required ICU admission and 9.80% of them needed mechanical breathing. Analyzing the clinical and epidemiological features of SARI patients can aid in better comprehending and controlling the outbreak. To stop the infection from spreading widely throughout the community, quarantine and close observation will be necessary.
J. Gayathri and M.K. Suresh. SARS-CoV-2's Clinical and Epidemiological Profile in Patients Suffering from Severe Acute Respiratory Illness (SARI) at a North Indian Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.326.329
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.326.329