Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Antimicrobial drugs play a crucial role in preventing postoperative infections, particularly in otorhinolaryngology (ENT) surgeries, where the risk of surgical site infections (SSIs) is high. Proper antimicrobial utilization is essential for reducing complications such as prolonged hospital stays and antimicrobial resistance (AMR). This study aimed to evaluate the patterns of antimicrobial drug use in postoperative ENT patients in a government hospital setting, identifying gaps in practice and promoting rational drug use. This prospective, cross‐sectional, observational study was conducted over 12 months in the Department of Otorhinolaryngology at a government hospital in India. A total of 300 postoperative patients who underwent ENT surgeries and received antimicrobial therapy were included. Antimicrobial use, co‐morbid conditions and adverse drug reactions (ADRs) were recorded. Data were analyzed using descriptive statistics and chi‐square tests to assess associations between drug use, patient demographics and clinical outcomes. The most frequently prescribed antimicrobials were Amoxicillin+Clavulanic acid (16.25%), followed by Cephalosporins (26.61%) and Fluoroquinolones (6.72%). Males (57.33%) had a higher overall antimicrobial use compared to females (42.67%). Hypertension (25%) and diabetes mellitus (18.75%) were the most prevalent co‐morbidities. Adverse drug reactions were observed in 34% of the patients, with nausea and vomiting being the most common. No significant gender differences in antimicrobial use or ADRs were found. Antimicrobials are widely used in postoperative ENT patients, with penicillin’s and cephalosporins being the most common. The study highlights the need for adherence to antimicrobial stewardship programs to minimize inappropriate use and prevent antimicrobial resistance. Optimizing drug selection and duration of therapy can improve patient outcomes and reduce the incidence of ADRs.
How to cite this article:
Hemantkumar Ramdas Borse. Antimicrobial Utilization Patterns and Postoperative Outcomes in Otorhinolaryngology: A Prospective Observational Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.22.27
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.22.27