Early preterm neonates (28‐32 weeks gestation) face high rates of mortality and morbidity due to complications such as respiratory distress syndrome (RDS), sepsis and hyperbilirubinemia. This study aims to assess survival rates and short‐term clinical outcomes of early preterm neonates admitted to a tertiary care hospital's neonatal intensive care unit (NICU). A prospective observational study was conducted over 30 months (December 2021 to June 2024) in the NICU of a tertiary care hospital. A total of 408 preterm neonates born between 28 and 32 weeks gestation were enrolled. Data on maternal characteristics, neonatal outcomes, complications and NICU stay were collected. Statistical analysis was performed using SPSS version 20, with a p‐value<0.05 considered statistically significant. The overall survival rate was 67.16%, with a mortality rate of 30.15%. Respiratory distress syndrome was the most common complication, affecting 63.73% of neonates, followed by hyperbilirubinemia (48.53%) and sepsis (45.83%). The mean NICU stay was 4‐6 weeks for most neonates (34.06%). Maternal factors such as gravida status and antenatal care visits were not significantly associated with neonatal survival. Early preterm neonates continue to face high morbidity and mortality rates, primarily due to RDS and sepsis. Antenatal care, including corticosteroid administration, plays a crucial role in improving outcomes. More comprehensive prenatal interventions and improved NICU protocols are essential to reduce complications and improve survival rates in this vulnerable population.
Shobhit Kamble, Arvind N. Chavan, Saleem H. Tambe, Saurav Mallick, Sarfaraz Ahmed and Shital Narayan Rathod. Clinical Outcome Profile of Early Preterm Neonates in a NICU at Tertiary Care Center.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.114.118
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.114.118