Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Significance of serum blood lactate levels in critically ill patients to help clinicians in risk stratification and to predict mortality. Prospective non‐interventional observation study, where concentration of serum blood lactate levels were assessed in 100 critically ill patients at every 6th hour till the patient is deemed clinically stable or deceased, who presented to ED and admitted to critical care unit of SSIMS and RC, Davanagere for a period of two years. Serial serum lactate levels associated with patient outcome and 7 day mortality were compared. A significant finding was that of total 33 patients who did not survive, 32 patients had lactate >5mmol/L. However 67 patients who were survivors, 31 patients whose serum lactate levels >5mmol/L had a longer stay at the hospital for >7 days. High numbers of deaths were seen in sepsis, trauma cases. All respiratory failure cases survived. Survivability was highest in other medical emergencies in MICU where blood lactate levels were <5mmol/L. Decrease in serum lactate levels with time was consistently related with lower mortality rates in every group of patients. Statistically significant difference was observed between serum lactate levels related to length of stay in the hospital and mortality, with serial blood lactate levels measured beyond 6 hours from time of admission. Hyperlactatemia is common in critically ill patients. In critically ill patients, increased glycolysis may be a prime cause of raised blood lactate levels. Nevertheless, the increasing serial blood lactate levels have important significance in predicting morbidity and mortality or longer length of hospital stay in hyperlactatemia patients consistent with our results in this study.
How to cite this article:
Santhosh S. Ujjanappa, R. Rajesh and Rajat Pandarinath Naik. Study on Clinical Use of Serum Blood Lactate Monitoring in Critically ill Patients.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.572.578
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.572.578