files/journal/2022-09-03_18-51-40-000000_599.png

Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
138
Views
11
Downloads

Evaluating the Relationship Between Clinical Variables and Patient Outcomes in Snakebite Incidents

Dinesh Singh Mahor, Divyansh Gupta and Ritesh Yadav
Page: 394-400 | Received 25 Aug 2024, Published online: 30 Sep 2024

Full Text Reference XML File PDF File

Abstract

Snakebite envenoming poses a significant public health challenge, particularly in tropical regions. Effective clinical management is complicated by variations in venom composition, patient responses and treatment timing. This study aims to elucidate the relationships between clinical features and outcomes in snakebite patients to enhance treatment protocols and reduce mortality. This retrospective, observational study was conducted at SRVS Medical College, Shivpuri, using medical records of patients admitted with snakebites. Data collected included demographics, time to hospital arrival, ASV vials administered, hospitalization duration and presence of complications such as neurotoxicity and hematotoxicity. Statistical analyses included correlation, logistic regression and chi‐square tests to determine significant predictors of mortality and discharge. A significant positive correlation (r=0.758) was found between the number of ASV vials and hospitalization duration. Younger age was associated with fewer ASV vials (r=‐0.033) and shorter hospital stays (r=‐0.132). Neurotoxicity and hematotoxicity showed moderate positive correlations with the need for blood products (r=0.340 and r=0.320, respectively) and mechanical ventilation (r=0.390 and r=0.350, respectively). Logistic regression identified the number of ASV vials (OR=1.5 per vial) and neurotoxicity (OR=3.12) as significant predictors of mortality. Early hospital arrival (p=0.054) and younger age (p=0.064) showed trends toward better outcomes. Prompt ASV administration and careful monitoring of neurotoxicity and hematotoxicity may improve outcomes for snakebite patients. Younger age and timely first aid could enhance recovery rates. These findings suggest that standardized interventions tailored to the severity of envenomation and improved record‐keeping in under‐resourced areas could optimize patient management and outcomes. Future research should refine ASV protocols and first aid measures.


How to cite this article:

Dinesh Singh Mahor, Divyansh Gupta and Ritesh Yadav. Evaluating the Relationship Between Clinical Variables and Patient Outcomes in Snakebite Incidents.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.394.400
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.394.400