Blood is an intrinsic requirement for health care and blood transfusion service is the integral part of healthcare system throughout the world. The aim of blood transfusion service should be to provide effective blood and blood products which are as safe as possible and adequate to meet patient’s need. During the blood transfusion, transmission of infectious diseases through donated blood is an alarming situation and the causative agents can be virus, bacteria or protozoa. The World Health Organization (WHO) recommends all blood donations should be screened for evidence of infection prior to the release of blood and blood components for clinical or manufacturing use for the pursuit of global blood safety. After this routine serological screening implementation, the Transfusion‐transmissible infections (TTIs) have been drastically reduced in many countries. To determine the seroprevalence of Transfusion Transmitted Infections (TTIs) and to evaluate trends in TTIs among blood donors The present study was carried out in Blood center, Department of Pathology, Banas Medical college and Research Institute, Palanpur from January 2021 to December 2023. A total number of 4277 donors were screened for HIV, HBV, HCV by ELISA and syphilis and malaria by rapid method. Out of 4277 donors, 100% were males. Among these 0.86 % were reactive for transfusion transmitted infection. The major infections identified were syphilis (0.56%), HBV (0.16%), HIV (0.07%), and HCV (0.07%). No donors tested positive for malaria. Seropositivity for HBV, HCV, HIV, syphilis and malaria among the healthy donors indicates the risk or chance of acquisition of these infections during blood transfusion. Implementation of donor selection criteria should be strict and proper to minimize transfusion transmitted infections and provide safer blood and blood products.
Varshaben K. Dhuliya, Hiral P. Shah, Manjula J. Babariya, Monika Shroff and Rippal Kumar Bhimani. Prevalence of Transfusion Transmitted Diseases in Blood Donors in Tertiary Care Centre.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.199.201
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.199.201