Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Dexmedetomidine With Bupivacaine and Dexamethasone with Bupivacaine for Prolongation of Postoperative Analgesia Under Infraclavicular Brachial Plexus Block in Upper Limb Orthopaedic Surgery: A Prospective Comparative Observational Study
Sunita Shende, Sarita Thanekar, Aditya Velhal and Raviraj Pol
Page: 311-316 | Received 17 Jun 2023, Accepted 29 Jun 2023, Published online: 03 Jul 2023
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Abstract
Infraclavicular brachial plexus block is used for Upper extremity surgeries. Dexmedetomidine is a highly selective α‐2 adrenergic agonist that prolongs the duration of sensory and motor block and provide prolonged postoperative analgesia. Dexamethasone, a long‐acting glucocorticoid (t1/2 >36 hrs) has potent anti‐inflammatory and analgesic effects and prolongs postoperative analgesia. Hence, the present study was aimed to evaluate the effect of dexamethasone and dexmedetomidine on the onset and duration of anesthesia and duration of analgesia. Study was conducted to study the effect of dexmedetomidine with bupivacaine and dexamethasone with bupivacaine for prolongation of postoperative analgesia in infraclavicular brachial plexus block in upper limb orthopedic surgery. The study was done in 50 patients each in group dexmedetomidine (A) and dexamethasone (B). Group A received 0.25% bupivacaine (15 mL of 0.5% bupivacaine diluted to 30 cc) plus 50 μg of dexmedetomidine (1 mL) plus 1 mL distilled water (total volume 32 mL) and GROUP B was those who received 0.25% bupivacaine (15 mL of 0.5% bupivacaine diluted to 30 cc) plus 2 cc of dexamethasone. Duration of sensory and motor blockade was longer in dexamethasone group compared to dexmedetomidine. The time taken for the procedure, the onset of sensory blockade and motor blockade were noted. Onset of sensory and motor was earlier in group dexmedetomidine group. Duration of sensory and motor blockade was longer in dexamethasone group compared to dexmedetomidine (p<0.001). We conclude that onset of sensory and motor blockade is faster in dexmedetomidine group compared to dexamethasone group but duration of sensory and motor blockade is prolonged in dexamethasone group. Postoperative anaesthesia is prolonged in dexmeditomedine group.
How to cite this article:
Sunita Shende, Sarita Thanekar, Aditya Velhal and Raviraj Pol. Dexmedetomidine With Bupivacaine and Dexamethasone with Bupivacaine for Prolongation
of Postoperative Analgesia Under Infraclavicular Brachial Plexus Block in Upper Limb Orthopaedic Surgery: A Prospective Comparative Observational Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2023.311.316
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2023.311.316