Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
A total of 53 cases of leprosy diagnosed clinically attending the out patient department of Dermatology, Venereology, Leprology included in the present observational study. Maximum incidence of leprosy was seen in the age group of 21‐40 years (66%). Patients of both sexes were affected with predominance of males (73.6%) with a male to female ratio of 2.79:1. The most of the cases were daily wage manual labourers (47.2%) by occupation and were poor (62.26%). 60.4% were from rural area and 39.6% were from urban area. Majority of the patients were illiterates (66%), with 34% literate patients. Most of the patients in this study were married (69.8%). Skin lesions (90.6%), Tingling and numbness (32.1%) were the most common presenting complaints. 3.8% cases presented with deformity. Hypopigmented patches (66%) was the most common skin lesion, followed by erythematous patches and plaque/nodules type lesions in 41.5% cases. 7.5% of cases had satellite lesions. Most of the patients had impaired sensations (92.5%) over the lesions. Multiple asymmetrical nerve thickening was seen in 26.4% of cases. Both clinically and histopathologically BT constituted the predominant group (37.7%) and (32.1%) respectively. Fite Faraco staining of the biopsy specimen was positive in 91.67% cases of LL and negative in all cases of TT and BB. In the other spectrum it was variable. The overall clinico‐histopathological correlation was seen in 67.92% and a good concordance was seen in LL (83.33%%) followed by TT (66.67%) The least concordance was seen in BB (33.33%). Thus, some degree of overlap between different types of leprosy both clinically and histopathologically. Correlation of Clinical and Histopathological examination appears to be more useful in definite diagnosis and this in turn helps ineffective treatment and prevention of deformities.
How to cite this article:
Vasepalli Ramachandra Reddy, Ravipati Haritha and B. Sudha Madhuri. A Clinical and Pathological Prospective Study on Leprosy.
DOI: https://doi.org/10.36478/10.36478/makrjms.2022.4.116.119
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2022.4.116.119